Rosmanol
CAS No. 80225-53-2
Rosmanol ( Rosmanol )
Catalog No. M19118 CAS No. 80225-53-2
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 132 | In Stock |
|
10MG | 205 | In Stock |
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25MG | 430 | In Stock |
|
50MG | 619 | In Stock |
|
100MG | 861 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameRosmanol
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NoteResearch use only, not for human use.
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Brief DescriptionRosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis.
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DescriptionRosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.
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SynonymsRosmanol
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorAntioxidant; COX-2
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Research Area——
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Indication——
Chemical Information
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CAS Number80225-53-2
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Formula Weight346.42
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Molecular FormulaC20H26O5
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Purity98%
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Solubility——
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SMILESCC(C)c1cc2[C@H](O)[C@H]3OC(=O)[C@@]4(CCCC(C)(C)[C@H]34)c2c(O)c1O
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Chemical Name(4bR,8aS,9S,10S)-3,4,10-trihydroxy-2-isopropyl-8,8-dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epoxymethano)phenanthren-12-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Abdelhalim A, et al. Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis [J]. J Pharm Pharm Sci. 2015;18(4):448-59.
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