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Roflumilast
CAS No. 162401-32-3
Roflumilast ( B 9302-107; BY 217; BYK 20869; Daxas )
Catalog No. M12400 CAS No. 162401-32-3
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
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| 10MG | 60 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 170 | In Stock |
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| 100MG | 238 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameRoflumilast
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NoteResearch use only, not for human use.
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Brief DescriptionRoflumilast is a phosphodiesterase-4 (PDE-4) inhibitor.
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DescriptionRoflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.
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SynonymsB 9302-107; BY 217; BYK 20869; Daxas
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE4A1; PDE4A4; PDE4B1; PDE4B2; PDE4C1
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number162401-32-3
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Formula Weight403.21
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Molecular FormulaC17H14Cl2F2N2O3
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Purity>98%(HPLC)
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SolubilityEthanol: 15 mg/mL (37.2 mM); DMSO: 81 mg/mL (200.88 mM)
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SMILESO=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
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Chemical Name3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Barone FC, et al. Pharmacology. 2007 Aug 28;81(1):11-17.
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