Robinin

CAS No. 301-19-9

Robinin( EINECS 206-113-3 | NSC 9222 | Robinin )

Catalog No. M19350 CAS No. 301-19-9

Robinin is a flavone glycoside based on kaempferol.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Robinin
  • Note
    Research use only, not for human use.
  • Brief Description
    Robinin is a flavone glycoside based on kaempferol.
  • Description
    Robinin is a flavone glycoside based on kaempferol.
  • In Vitro
    Western Blot Analysis Cell Line:hPBMCs Concentration:6 μg/mL Incubation Time:24 h Result:Inhibited the upregulated expression of MCP 1, TNF-α, IL-6 and ICAM-1 with anti-inflammatory properties.Cell Viability Assay Cell Line: hPBMCs Concentration:1 μg/mL, 2 μg/mL,4 μg/mL,6 μg/mL,8 μg/mL,10 μg/mLIncubation Time:24 h Result:Concentration from 1 μg/ml-10 μg/ml on hPBMCs had no obvious cytotoxicity.RT-PCR Cell Line:hPBMCs Concentration:1 μg/mL, 2 μg/mL,4 μg/mL,6 μg/mL,8 μg/mL,10 μg/mL Incubation Time:24 h Result:Inhibited the upregulated expression of TLR2 and TLR4.Cell Proliferation Assay Cell Line:Mia-PACA2 and PANC-1 Concentration:1 μM Incubation Time:24 h Result:Inhibited cell proliferation.Cell Migration Assay Cell Line:Mia-PACA2 and PANC-1 Concentration:1 μM Incubation Time:24 h Result:Decreased the cell migration area
  • In Vivo
    Animal Model:Adjuvant arthritis mice model Dosage:50 mg/kg Robinin and 0.3 mg/kg MTX twice a week Administration:Oral gavage (p.o.)Result:Had anti-inflammatory and anti-arthritic action.Animal Model:Sprague Dawley rats model Dosage:50 mg/kg Robinin for 10 days Administration:Oral gavage (p.o.)Result:Reduced the cardiotoxic effects of Doxorubicin-induced
  • Synonyms
    EINECS 206-113-3 | NSC 9222 | Robinin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    301-19-9
  • Formula Weight
    740.66
  • Molecular Formula
    C33H40O19
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (337.54 mM)
  • SMILES
    C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)C6=CC=C(C=C6)O)O)O)O)O)O)O
  • Chemical Name
    3-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl)oxy)-7-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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