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Rimeporide

CAS No. 187870-78-6

Rimeporide ( EMD87580;EMD-87580 )

Catalog No. M12914 CAS No. 187870-78-6

Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Rimeporide
  • Note
    Research use only, not for human use.
  • Brief Description
    Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor.
  • Description
    Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor, show promise as potential therapeutic agents for the treatment of heart failure.Heart Failure Discontinued
  • Synonyms
    EMD87580;EMD-87580
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    NHE-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    187870-78-6
  • Formula Weight
    333.38
  • Molecular Formula
    C11H15N3O5S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 15 mg/mL,50 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    CC1=CC(=C(C=C1C(=O)NC(=N)N)S(=O)(=O)C)S(=O)(=O)C
  • Chemical Name
    N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cox CS Jr, et al. Chest. 2003 Jan;123(1):187-94.
2. Corvera JS, et al .Ann Thorac Surg. 2003 Nov;76(5):1614-22.
3. Chen L, et al. Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H381-7.
4. Javadov S, et al. J Mol Cell Cardiol. 2005 Jan;38(1):135-43.
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