Ridinilazole ( SMT19969 )

Catalog No. M22106 CAS No. 308362-25-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Ridinilazole
Note

Research use only, not for human use.
Brief Description

Ridinilazole is a novel narrow-spectrum nonabsorbable antibiotic.
Description

Ridinilazole is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90?=?8 mg/L) or vancomycin (MIC90?=?2 mg/L).ridinilazole , a novel antibacterial currently under development for the treatment of CDI.?Owing to its highly targeted spectrum of activity and ability to spare the normal gut microbiota, ridinilazole provides significant advantages over metronidazole and vancomycin, the mainstay antibiotics for CDI.?Ridinilazole is bactericidal against C. difficile and exhibits a prolonged post-antibiotic effect.?Furthermore, treatment with ridinilazole results in decreased toxin production.
Synonyms

SMT19969
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

Immune system
Indication

Clostridium Difficile Infection

1.Vickers RJ, et al. Ridinilazole: a novel therapy for Clostridium difficile infection. Int J Antimicrob Agents. 2016 Aug;48(2):137-43.

Calculator

molnova catalog