Cart
sales@molnova.com
Rhapontigenin
CAS No. 500-65-2
Rhapontigenin ( —— )
Catalog No. M18663 CAS No. 500-65-2
Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | In Stock |
|
| 10MG | 166 | In Stock |
|
| 25MG | 321 | In Stock |
|
| 50MG | 483 | In Stock |
|
| 100MG | 605 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRhapontigenin
-
NoteResearch use only, not for human use.
-
Brief DescriptionRhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.
-
DescriptionRhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
RecptorCYP1A1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number500-65-2
-
Formula Weight258.3
-
Molecular FormulaC15H14O4
-
Purity98%
-
Solubility——
-
SMILESCOc1c(cc(cc1)/C=C/c1cc(cc(c1)O)O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Jo SP1, Kim JK2, Lim YH1.Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet.Planta Med. 2014 Aug;80(13):1067-71.
molnova catalog
related products
-
Cornuside
Cornuside has immunomodulatory activity.Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells.
-
JHU 37160
JHU 37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.
-
Adenine
Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.
