Cart
sales@molnova.com
Rezatapopt
CAS No. 2636846-41-6
Rezatapopt( —— )
Catalog No. M37295 CAS No. 2636846-41-6
Rezatapopt (PC14586) is a small molecule p53 reactivator with anti-tumor activity that selectively binds to the cleft present in the TP53 Y220C mutant protein and restores the p53 wild-type (normal) conformation and transcriptional activity, and can be used to study locally advanced or metastatic solid tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 922 | Get Quote |
|
| 50MG | 1702 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameRezatapopt
-
NoteResearch use only, not for human use.
-
Brief DescriptionRezatapopt (PC14586) is a small molecule p53 reactivator with anti-tumor activity that selectively binds to the cleft present in the TP53 Y220C mutant protein and restores the p53 wild-type (normal) conformation and transcriptional activity, and can be used to study locally advanced or metastatic solid tumors.
-
DescriptionRezatapopt is an antineoplastic agent, used to inhibit solid tumor with p53 mutation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
Targetp53
-
Recptorp53
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2636846-41-6
-
Formula Weight545.57
-
Molecular FormulaC28H31F4N5O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C1=C2C(N(CC(F)(F)F)C(C#CCNC3=C(OC)C=C(C(NC)=O)C=C3)=C2)=CC=C1)[C@H]4[C@@H](F)CN(C)CC4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li Sujing, et al. Heteroarylalkyne compounds for targeting mutant of p53 and their preparation. World Intellectual Property Organization, WO2023016434 A1. 2023-02-16.
molnova catalog
related products
-
DPBQ
DPBQ is a factor that activates p53.
-
Importazole
Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
-
Pifithrin-α
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes.
