Reversine

CAS No. 656820-32-5

Reversine( Reversine. )

Catalog No. M15499 CAS No. 656820-32-5

Reversine, a small synthetic purine analogue (2,6-disubstituted purine), is a potent inhibitior of Aurora A/B/C with IC50s of 150-500 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 58 In Stock
10MG 73 In Stock
25MG 150 In Stock
50MG 212 In Stock
100MG 372 In Stock
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Biological Information

  • Product Name
    Reversine
  • Note
    Research use only, not for human use.
  • Brief Description
    Reversine, a small synthetic purine analogue (2,6-disubstituted purine), is a potent inhibitior of Aurora A/B/C with IC50s of 150-500 nM.
  • Description
    Reversine, a small synthetic purine analogue (2,6-disubstituted purine), is a potent inhibitior of Aurora A/B/C with IC50s of 150-500 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Reversine.
  • Pathway
    Apoptosis
  • Target
    Adenosine Receptor
  • Recptor
    A3| Aurora A| Aurora B| Aurora C
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    656820-32-5
  • Formula Weight
    393.49
  • Molecular Formula
    C21H27N7O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 5 mg/mL warmed (12.71 mM)
  • SMILES
    C1CCC(CC1)Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2[nH]cnc12
  • Chemical Name
    N6-cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.D'Alise AM, et al. Mol Y Ther. 2008, 7(5), 1140-1149.
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