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Resistomycin

CAS No. 20004-62-0

Resistomycin( —— )

Catalog No. M33761 CAS No. 20004-62-0

Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 166 Get Quote
5MG 238 Get Quote
10MG 352 Get Quote
25MG 546 Get Quote
50MG 734 Get Quote
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Biological Information

  • Product Name
    Resistomycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.
  • Description
    Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis.
  • In Vitro
    Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation.Resistomycin displays a high affinity for GST-Pellino-1 (KD = 2.58 μM) as indicated by surface plasmon resonance. Resistomycin treatment reduced the expression of SNAIL and SLUG in TNBC cells.Resistomycin induced apoptosis and cycle arrest in human hepatocellular carcinoma cells by activating p38 MAPK pathway in vitro and in vivo.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    20004-62-0
  • Formula Weight
    376.36
  • Molecular Formula
    C22H16O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1cc(O)c2C(=O)c3c(O)cc(O)c4C(=O)C(C)(C)c5cc(O)c1c2c5-c34
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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