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Raloxifene

CAS No. 84449-90-1

Raloxifene( Pharoxifene | Raloxifenum | Keoxifene | LY-139481 )

Catalog No. M24833 CAS No. 84449-90-1

Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Raloxifene
  • Note
    Research use only, not for human use.
  • Brief Description
    Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
  • Description
    Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
  • In Vitro
    ——
  • In Vivo
    Raloxifene (4?mg/kg; intragastrically; daily for 13 weeks) significantly prevents bone loss in ovariectomized (OVX) rats. Animal Model:Female, 12-week-old, Wistar rats (OVX rats) Dosage:4?mg/kg Administration:Intragastrically; daily for 13 weeks Result:Significantly increased the levels of E2 in OVX rats and significantly decreased the levels of BGP.
  • Synonyms
    Pharoxifene | Raloxifenum | Keoxifene | LY-139481
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SERM
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    84449-90-1
  • Formula Weight
    473.58
  • Molecular Formula
    C28H27NO4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:90 mg/mL (190.04 mM; Need ultrasonic)；Ethanol:9 mg/mL (19.00 mM; Need ultrasonic)
  • SMILES
    Oc(cc1)ccc1-c1c(C(c(cc2)ccc2OCCN2CCCCC2)=O)c(ccc(O)c2)c2s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439.
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