RVD-Hpα ( )

Catalog No. M30820 CAS No. 1193362-76-3

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Product Name

RVD-Hpα
Note

Research use only, not for human use.
Brief Description

N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. Increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. Also high affinity CB2 positive allosteric modulator (Ki = 50 nM).
Description

N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. Increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. Also high affinity CB2 positive allosteric modulator (Ki = 50 nM).
Synonyms
Pathway

GPCR/G Protein
Target

Cannabinoid Receptor
Recptor

——
Research Area

——
Indication

——

CAS Number

1193362-76-3
Formula Weight

1424.7
Molecular Formula

C65H105N19O17
Purity

>98% (HPLC)
Solubility

water:1 mg/mL
SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(O)=O
Chemical Name

1. Gomes et al (2009) Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 23 3020 PMID:

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