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RO-0335
CAS No. 867365-76-2
RO-0335( —— )
Catalog No. M24875 CAS No. 867365-76-2
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 110 | In Stock |
|
| 10MG | 178 | In Stock |
|
| 25MG | 410 | In Stock |
|
| 50MG | 605 | In Stock |
|
| 100MG | 860 | In Stock |
|
| 500MG | 1728 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRO-0335
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NoteResearch use only, not for human use.
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Brief DescriptionRO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor.
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DescriptionRO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetReverse Transcriptase
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RecptorReverse Transcriptase
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Research Area——
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Indication——
Chemical Information
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CAS Number867365-76-2
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Formula Weight573.22
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Molecular FormulaC21H13BrCl2FN3O4S
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Purity>98% (HPLC)
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SolubilityDMSO:200mg/ml(348.91mM; need ultrasonic)
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SMILESNS(c(cc1)cc(Cl)c1NC(Cc(ccc(Br)c1Oc2cc(Cl)cc(C#N)c2)c1F)=O)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Javanbakht H , Ptak R G , Chow E , et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor[J]. Antiviral Research, 2010, 86(2):212-219.
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