RIPK1-IN-9

CAS No. 2682889-57-0

RIPK1-IN-9( —— )

Catalog No. M35690 CAS No. 2682889-57-0

RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 547 Get Quote
5MG 823 Get Quote
10MG 1131 Get Quote
25MG 1628 Get Quote
50MG 2190 Get Quote
100MG 2898 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    RIPK1-IN-9
  • Note
    Research use only, not for human use.
  • Brief Description
    RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.
  • Description
    RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    RIP kinase
  • Recptor
    RIP kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2682889-57-0
  • Formula Weight
    472.51
  • Molecular Formula
    C26H25FN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C=2C(=NC=C(C2)C3=CC=4N(C=C3)N=C(N)N4)CCN1CC5=C(OC6CCCC6)C=CC(F)=C5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.
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