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RIPA-56
CAS No. 1956370-21-0
RIPA-56( RIPA56 | RIPA 56 )
Catalog No. M13064 CAS No. 1956370-21-0
A highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | Get Quote |
|
| 10MG | 43 | Get Quote |
|
| 25MG | 77 | Get Quote |
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| 50MG | 124 | Get Quote |
|
| 100MG | 203 | Get Quote |
|
| 200MG | 300 | Get Quote |
|
| 500MG | 503 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRIPA-56
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM.
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DescriptionA highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM; shows good selectivity in kinase panel screening, and does not IDO activity ( at >200 uM); efficiently protects mice from mTNFα-induced multi-organ damage.
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In Vitro——
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In Vivo——
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SynonymsRIPA56 | RIPA 56
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PathwayApoptosis
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TargetRIP kinase
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RecptorRIP kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number1956370-21-0
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Formula Weight221.29546
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Molecular FormulaC13H19NO2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCCC(C)(C)C(N(O)CC1=CC=CC=C1)=O
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Chemical NameButanamide, N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ren Y, et al. J Med Chem. 2017 Feb 9;60(3):972-986.
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