RIG012
CAS No. 2642218-43-5
RIG012( —— )
Catalog No. M36533 CAS No. 2642218-43-5
RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM (measured by NADH-coupled ATPase), and it inhibits the expression of IFN-β and ISG hRsad2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 176 | In Stock |
|
| 5MG | 275 | In Stock |
|
| 10MG | 440 | In Stock |
|
| 25MG | 702 | In Stock |
|
| 50MG | 908 | In Stock |
|
| 100MG | 1242 | In Stock |
|
| 500MG | 2502 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRIG012
-
NoteResearch use only, not for human use.
-
Brief DescriptionRIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM (measured by NADH-coupled ATPase), and it inhibits the expression of IFN-β and ISG hRsad2.
-
DescriptionRIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2642218-43-5
-
Formula Weight359.42
-
Molecular FormulaC23H21NO3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 33.33 mg/mL (92.73 mM; Ultrasonic )
-
SMILESC(C)C1(CC)C=2C(C=3C(C(=O)C2OCC4=CC=CC=C4)=CC=CC3)=NC1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317.?
molnova catalog
related products
-
Triacontanoic Acid
Triacontanoic Acid belongs to the class of organic compounds known as very long-chain fatty acids.?
-
Biotin LC hydrazide
Biotin LC hydrazide (BACH) is a modification reagent of long-chain protein. Biotin LC hydrazide transforms periodate-oxidized glycoproteins and can be used to target glycoproteins and glycans.
-
CTP Synthetase-IN-1
CTP Synthetase-IN-1 is an orally active and potent cytidine 5'-triphosphate synthetase (CTPS) inhibitor with potential antitumour activity, shows anti-inflammatory activity in animal models of inflammation, inhibits human CTPS1 and human CTPS2, and can be used in studies of arthritis and rheumatoid arthritis.
Cart
sales@molnova.com