RET-IN-1 ( —— )

Catalog No. M21830 CAS No. 2222755-14-6

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Datasheet

HNMR

HPLC

MSDS

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Product Name

RET-IN-1
Note

Research use only, not for human use.
Brief Description

RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
Description

RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

2222755-14-6
Formula Weight

553.255
Molecular Formula

C29H31N9O3
Purity

>98% (HPLC)
Solubility

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SMILES

N#CC1=C2C(C3=NC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OC[C@H]7CNCCO7)=CN2N=C1
Chemical Name

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