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Quetiapin

CAS No. 111974-69-7

Quetiapin ( —— )

Catalog No. M10429 CAS No. 111974-69-7

Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Quetiapin
  • Note
    Research use only, not for human use.
  • Brief Description
    Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder.
  • Description
    Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT; mAChR; Adrenergic Receptor; Dopamine; H1 receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    111974-69-7
  • Formula Weight
    383.51
  • Molecular Formula
    C21H25N3O2S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 36 mg/mL;Water: <1 mg/mL
  • SMILES
    OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nasrallah HA. Mol Psychiatry. 2008 Jan;13(1):27-35.
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