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Quassin

CAS No. 76-78-8

Quassin( —— )

Catalog No. M31061 CAS No. 76-78-8

Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Quassin
  • Note
    Research use only, not for human use.
  • Brief Description
    Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.
  • Description
    Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.
  • In Vitro
    Quassin (Compound 1; 5-25 ng/mL) inhibits both the basal and luteinizing hormone-stimulated testosterone secretion of rat Leydig cells in a dose-dependent fashion.
  • In Vivo
    Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats. Animal Model:35 females albino rats (150-170 g) .Dosage:0.1 mg/kg, 1.0 mg/kg and 2.0 mg/kg Administration:Oral administration; daily; for 60 daysResult:There was a significant decrease in the weight of the ovary and uterus in all the groups relative to the control. There was also a significant decrease in serum estrogen levels in quassin treated rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76-78-8
  • Formula Weight
    388.5
  • Molecular Formula
    C22H28O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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