Pyranine

CAS No. 6358-69-6

Pyranine( HPTS | Solvent Green 7 )

Catalog No. M24647 CAS No. 6358-69-6

Pyranine is reported as a new class of fluorescent chemosensor for the Cu+ ion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 41 In Stock
1G 71 In Stock

Biological Information

  • Product Name
    Pyranine
  • Note
    Research use only, not for human use.
  • Brief Description
    Pyranine is reported as a new class of fluorescent chemosensor for the Cu+ ion.
  • Description
    Pyranine is reported as a new class of fluorescent chemosensor for the Cu+ ion.
  • In Vitro
    Pyranine is capable of discriminating ranges of cations from the Cu+ ion, even in competing environment. Pyranine displays a rapid fluorescence response (t1/2=1.66 min) towards the Cu+ ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu+ is 2:1. The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH.
  • In Vivo
    ——
  • Synonyms
    HPTS | Solvent Green 7
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6358-69-6
  • Formula Weight
    524.39
  • Molecular Formula
    C16H7Na3O10S3
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:100 mg/mL (190.70 mM; Need ultrasonic);DMSO:25 mg/mL (47.67 mM; Need ultrasonic)
  • SMILES
    O=S(C1=C(C2=C34)C=CC4=C(O)C=C(S(=O)(O[Na])=O)C3=CC=C2C(S(=O)(O[Na])=O)=C1)(O[Na])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Saha T, et al. In vitro sensing of Cu(+) through a green fluorescence rise of pyranine. Photochem Photobiol Sci. 2014 Oct;13(10):1427-33.
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