Prucalopride
CAS No. 179474-81-8
Prucalopride ( Prucalopride; Prucalopride free base )
Catalog No. M12708 CAS No. 179474-81-8
Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively.
Purity : >98%(HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 29 | Get Quote |
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10MG | 47 | Get Quote |
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25MG | 61 | Get Quote |
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50MG | 73 | Get Quote |
|
100MG | 126 | Get Quote |
|
200MG | 178 | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NamePrucalopride
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NoteResearch use only, not for human use.
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Brief DescriptionPrucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively.
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DescriptionPrucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
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SynonymsPrucalopride; Prucalopride free base
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT1A; 5-HT1B; 5-HT3; 5-HT4A; 5-HT4B
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number179474-81-8
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Formula Weight367.87
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Molecular FormulaC18H26ClN3O3
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Purity>98%(HPLC)
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SolubilityEthanol: 38 mg/mL (103.29 mM); DMSO: 60 mg/mL (163.1 mM)
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SMILESClC1=CC(C(NC2CCN(CCCOC)CC2)=O)=C3C(CCO3)=C1N
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Chemical Name4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Homoeriodictyol
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells.In contrast to other polyphenols, the flavanon Homoeriodictyol promotes glucose uptake by 29.0 ± 3.83% at a concentration of 100 μM.
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GSK163090
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
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Chlorprothixene
Chlorprothixene is a typical antipsychotic drug of the thioxanthene class and was the first of the series to be synthesized.