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Prucalopride

CAS No. 179474-81-8

Prucalopride ( Prucalopride; Prucalopride free base )

Catalog No. M12708 CAS No. 179474-81-8

Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 47 Get Quote
25MG 61 Get Quote
50MG 73 Get Quote
100MG 126 Get Quote
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Biological Information

  • Product Name
    Prucalopride
  • Note
    Research use only, not for human use.
  • Brief Description
    Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively.
  • Description
    Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
  • Synonyms
    Prucalopride; Prucalopride free base
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT1A; 5-HT1B; 5-HT3; 5-HT4A; 5-HT4B
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    179474-81-8
  • Formula Weight
    367.87
  • Molecular Formula
    C18H26ClN3O3
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 38 mg/mL (103.29 mM); DMSO: 60 mg/mL (163.1 mM)
  • SMILES
    ClC1=CC(C(NC2CCN(CCCOC)CC2)=O)=C3C(CCO3)=C1N
  • Chemical Name
    4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Briejer MR, et al. Eur J Pharmacol, 2001, 423(1), 71-83.
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