Proxyphylline ( 7-(2-Hydroxypropyl)theophylline )

Catalog No. M20596 CAS No. 603-00-9

Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant vasodilator and bronchodilator.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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500MG	37	In Stock
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Biological Information

Product Name

Proxyphylline
Note

Research use only not for human use.
Brief Description

Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant vasodilator and bronchodilator.
Description

Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant vasodilator and bronchodilator.
Synonyms

7-(2-Hydroxypropyl)theophylline
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

adenosine A1/A2a receptor;PDE
Research Area

Cardiovascular Disease
Indication

Cerebral thrombus cerebral insufficiency coronary heart disease

Chemical Information

CAS Number

603-00-9
Formula Weight

238.24
Molecular Formula

C10H14N4O3
Purity

>98% (HPLC)
Solubility

DMSO:47 mg/mL (197.28 mM)
SMILES

CC(O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12
Chemical Name

7-(2-hydroxypropyl)-13-dimethyl-37-dihydro-1H-purine-26-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kukovetz W R G P?ch Holzmann S . Overadditive synergism between theophylline diprophylline and proxyphylline in tracheal smooth muscle relaxation[J]. Arzneimittel-Forschung 1983 33(10):1450-1454.

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