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Protostemonine

CAS No. 27495-40-5

Protostemonine( —— )

Catalog No. M18348 CAS No. 27495-40-5

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Protostemonine
  • Note
    Research use only, not for human use.
  • Brief Description
    Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo.
  • Description
    Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM.Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    27495-40-5
  • Formula Weight
    417.5
  • Molecular Formula
    C23H31NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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