Protogracillin

CAS No. 54848-30-5

Protogracillin ( —— )

Catalog No. M27957 CAS No. 54848-30-5

Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 129 Get Quote
5MG 222 Get Quote
10MG 331 Get Quote
25MG 536 Get Quote
50MG 777 Get Quote
100MG 1044 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Protogracillin
  • Note
    Research use only, not for human use.
  • Brief Description
    Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.
  • Description
    Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.(In Vitro):Paris polyphylla J.E. Smith is extensively used in traditional systems of Indian and Chinese medicines mainly for its anticancerous property. The national and international demand for P. polyphylla is constantly increasing and most of the supplies come from wild. Illegal and unscientific exploitation coupled with habitat destruction decreases the natural population of the herb, as a consequence this species comes under vulnerable category. Restoration and conservation of the natural population of this potential herb is prerequisites. METHODS AND RESULTS: This article aims to provide an overview on chemical and biological prospective of P. polyphylla. Secondary metabolites such as daucosterol, polyphyllin D, β -ecdysterone, Paris saponins I, II, V, VI, VII, H, dioscin, oligosaccharides, heptasaccharide, octasaccharide, trigofoenoside A, Protogracillin, Paris yunnanosides G-J, padelaoside B, pinnatasterone, formosanin C and 20-hydroxyecdyson saponins have been isolated from P. polyphylla. Several biological activities such as anticancerous, antitumor, cytotoxic, anthelmintic, antimicrobial, antiangiogenic, immunostimulating, contractile and hemostatic have also been reported. CONCLUSIONS: Consequently, this review will be helpful to the researcher and scientist for further research.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Ca(2+) receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54848-30-5
  • Formula Weight
    1065.2
  • Molecular Formula
    C51H84O23
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H]1[C@H](OC[C@H](C)CC[C@]2(O)[C@@H](C)[C@]3([H])[C@](CC4)(C)[C@](C[C@]3([H])O2)([H])[C@@]5([H])[C@@]4([H])[C@](CC[C@H](O[C@H](O[C@H](CO)[C@H]6O)[C@H](O[C@H](O[C@H]7C)[C@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]([C@H](O)[C@H]8O)O[C@H](CO)[C@H]8O)C9)(C)C9=CC5)O[C@H](CO)[C@H]([C@@H]1O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14.
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