Protogracillin
CAS No. 54848-30-5
Protogracillin ( —— )
Catalog No. M27957 CAS No. 54848-30-5
Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 129 | Get Quote |
|
5MG | 222 | Get Quote |
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10MG | 331 | Get Quote |
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25MG | 536 | Get Quote |
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50MG | 777 | Get Quote |
|
100MG | 1044 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameProtogracillin
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NoteResearch use only, not for human use.
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Brief DescriptionProtogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.
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DescriptionProtogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.(In Vitro):Paris polyphylla J.E. Smith is extensively used in traditional systems of Indian and Chinese medicines mainly for its anticancerous property. The national and international demand for P. polyphylla is constantly increasing and most of the supplies come from wild. Illegal and unscientific exploitation coupled with habitat destruction decreases the natural population of the herb, as a consequence this species comes under vulnerable category. Restoration and conservation of the natural population of this potential herb is prerequisites. METHODS AND RESULTS: This article aims to provide an overview on chemical and biological prospective of P. polyphylla. Secondary metabolites such as daucosterol, polyphyllin D, β -ecdysterone, Paris saponins I, II, V, VI, VII, H, dioscin, oligosaccharides, heptasaccharide, octasaccharide, trigofoenoside A, Protogracillin, Paris yunnanosides G-J, padelaoside B, pinnatasterone, formosanin C and 20-hydroxyecdyson saponins have been isolated from P. polyphylla. Several biological activities such as anticancerous, antitumor, cytotoxic, anthelmintic, antimicrobial, antiangiogenic, immunostimulating, contractile and hemostatic have also been reported. CONCLUSIONS: Consequently, this review will be helpful to the researcher and scientist for further research.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCa(2+) receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number54848-30-5
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Formula Weight1065.2
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Molecular FormulaC51H84O23
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Purity>98% (HPLC)
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Solubility——
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SMILESO[C@H]1[C@H](OC[C@H](C)CC[C@]2(O)[C@@H](C)[C@]3([H])[C@](CC4)(C)[C@](C[C@]3([H])O2)([H])[C@@]5([H])[C@@]4([H])[C@](CC[C@H](O[C@H](O[C@H](CO)[C@H]6O)[C@H](O[C@H](O[C@H]7C)[C@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]([C@H](O)[C@H]8O)O[C@H](CO)[C@H]8O)C9)(C)C9=CC5)O[C@H](CO)[C@H]([C@@H]1O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14.
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