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Propargyl-PEG13-bromide

CAS No. 2055105-25-2

Propargyl-PEG13-bromide ( —— )

Catalog No. M27787 CAS No. 2055105-25-2

Propargyl-PEG13-bromide is a PEG derivative containing a propargyl group.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 68 Get Quote
5MG 87 Get Quote
10MG 141 Get Quote
25MG 255 Get Quote
50MG 357 Get Quote
100MG 518 Get Quote
200MG 704 Get Quote
500MG 1056 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    Propargyl-PEG13-bromide
  • Note
    Research use only, not for human use.
  • Brief Description
    Propargyl-PEG13-bromide is a PEG derivative containing a propargyl group.
  • Description
    Propargyl-PEG13-bromide is a PEG derivative containing a propargyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The bromide (Br) can be used in nucleophilic substitution reactions.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p53/MDM2;Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2055105-25-2
  • Formula Weight
    691.7
  • Molecular Formula
    C29H55BrO13
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang H, et al. A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells. Neoplasia. 2011 Jul;13(7):611-9.
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