Probimane ( Probimane; probimane; AT-2153; Pro )

Catalog No. M17801 CAS No. 108093-90-9

Probimane had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.

Purity : 98%

COA

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Biological Information

Product Name

Probimane
Note

Research use only, not for human use.
Brief Description

Probimane had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.
Description

Probimane is anticancer agents. Pro is active against more categories of tumors both in vivo and in vitro, which in some circumstances may make it superior to the currently-used anticancer bisdioxopiperazines, including razoxane and MST-16.
Synonyms

Probimane; probimane; AT-2153; Pro
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

108093-90-9
Formula Weight

466.54
Molecular Formula

C21H34N6O6
Purity

98%
Solubility

——
SMILES

CC(CN1CC(=O)N(C(=O)C1)CN1CCOCC1)N1CC(=O)N(C(=O)C1)CN1CCOCC1
Chemical Name

1-(Morpholin-4-ylmethyl)-4-[2-[4-(morpholin-4-ylmethyl)-3,5-dioxopiperazin-1-yl]propyl]piperazine-2,6-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lu DY, et al. Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines. BMC Pharmacol. 2005 Jun 20;5:11.

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