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Probenecid

CAS No. 57-66-9

Probenecid ( NSC 18786 )

Catalog No. M15105 CAS No. 57-66-9

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.

Purity : >98%(HPLC)

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HNMR

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MSDS

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Biological Information

Product Name

Probenecid
Note

Research use only, not for human use.
Brief Description

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.
Description

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Synonyms

NSC 18786
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRPV2
Research Area

Metabolic Disease
Indication

——

Chemical Information

CAS Number

57-66-9
Formula Weight

285.36
Molecular Formula

C13H19NO4S
Purity

>98%(HPLC)
Solubility

Ethanol: 22 mg/mL (77.09 mM); DMSO: 57 mg/mL (199.74 mM)
SMILES

CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O
Chemical Name

4-(dipropylsulfamoyl)benzoic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.McDonough PM, et al. Cell Calcium, 1989, 10(3), 171-180.

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