Pregnenolone ( NSC 1616; NSC 18158; 3β-hydroxy-5-Pregnen-20-one; Δ5-Pregnenolone )

Catalog No. M11947 CAS No. 145-13-1

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Product Name

Pregnenolone
Note

Research use only, not for human use.
Brief Description

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues.
Description

A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Synonyms

NSC 1616; NSC 18158; 3β-hydroxy-5-Pregnen-20-one; Δ5-Pregnenolone
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

mAChR
Research Area

Neurological Disease
Indication

——

CAS Number

145-13-1
Formula Weight

316.48
Molecular Formula

C21H32O2
Purity

>98%(HPLC)
Solubility

Ethanol: 22 mg/mL (69.51 mM); DMSO: 22 mg/mL (69.51 mM)
SMILES

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(C)=O
Chemical Name

1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one

1.Wong P, et al. Transl Psychiatry. 2015 Mar 17; 5:e528.

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