Pomalidomide-PEG3-CO2H

CAS No. 2138440-82-9

Pomalidomide-PEG3-CO2H( Thalidomide-NH-PEG3-propionic acid )

Catalog No. M28265 CAS No. 2138440-82-9

Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 34 Get Quote
5MG 54 Get Quote
10MG 79 Get Quote
25MG 132 Get Quote
50MG 239 Get Quote
100MG 446 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Pomalidomide-PEG3-CO2H
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
  • Description
    Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
  • In Vitro
  • In Vivo
  • Synonyms
    Thalidomide-NH-PEG3-propionic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TMEM16A
  • Research Area
  • Indication

Chemical Information

  • CAS Number
    2138440-82-9
  • Formula Weight
    477.46
  • Molecular Formula
    C22H27N3O9
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (261.80 mM)
  • SMILES
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hahn A, et al. Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium. Physiol Rep. 2017 Jun;5(12). pii: e13290.
molnova catalog
related products
  • 1,2-Dimethoxybenzene

    1,2-Dimethoxybenzene, a natural product secreted by Silene latifolia, is an effective pollinator attractant for the nocturnal moth Hadena bicruris.

  • Oxyphyllacinol

    Oxyphyllacinol has antidiarrheal activity.Oxyphyllacinol has been shown to treat dementia. Oxyphyllacinol was isolated from the S. nodiflora water fraction, while the S. nodiflora water fraction has been shown to have antioxidant and anti-aging activities, inducing mitochondrial activity and increasing ctt1 gene expression by regulating stress tolerance response.

  • BPTU

    Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle.