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Pomalidomide-PEG2-CO2H

CAS No. 2140807-17-4

Pomalidomide-PEG2-CO2H ( Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid )

Catalog No. M28267 CAS No. 2140807-17-4

Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 54 Get Quote
10MG 79 Get Quote
25MG 132 Get Quote
50MG 237 Get Quote
100MG 347 Get Quote
200MG 518 Get Quote
500MG Get Quote Get Quote
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Biological Information

  • Product Name
    Pomalidomide-PEG2-CO2H
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
  • Description
    Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
  • Synonyms
    Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2140807-17-4
  • Formula Weight
    433.4
  • Molecular Formula
    C20H23N3O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
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