Pomalidomide-PEG2-CO2H ( Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid )

Catalog No. M28267 CAS No. 2140807-17-4

Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	79	Get Quote
25MG	132	Get Quote
50MG	237	Get Quote
100MG	347	Get Quote
200MG	518	Get Quote
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Biological Information

Product Name

Pomalidomide-PEG2-CO2H
Note

Research use only, not for human use.
Brief Description

Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
Description

Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
Synonyms

Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid
Pathway

Others
Target

Other Targets
Recptor

EGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

2140807-17-4
Formula Weight

433.4
Molecular Formula

C20H23N3O8
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.

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