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Pomalidomide-PEG2-CO2H
CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H( Pomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid )
Catalog No. M28267 CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 54 | Get Quote |
|
| 10MG | 79 | Get Quote |
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| 25MG | 132 | Get Quote |
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| 50MG | 237 | Get Quote |
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| 100MG | 347 | Get Quote |
|
| 200MG | 518 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePomalidomide-PEG2-CO2H
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NoteResearch use only, not for human use.
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Brief DescriptionPomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
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DescriptionPomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
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In Vitro——
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In Vivo——
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SynonymsPomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid
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PathwayOthers
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TargetOther Targets
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RecptorEGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number2140807-17-4
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Formula Weight433.41
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Molecular FormulaC20H23N3O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (144.21 mM)
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SMILESO=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
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