Polygodial
CAS No. 6754-20-7
Polygodial ( Tadeonal )
Catalog No. M27687 CAS No. 6754-20-7
Polygodial is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 178 | Get Quote |
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10MG | 282 | Get Quote |
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25MG | 480 | Get Quote |
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100MG | Get Quote | Get Quote |
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200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NamePolygodial
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NoteResearch use only, not for human use.
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Brief DescriptionPolygodial is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.
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DescriptionPolygodial is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.(In Vitro):When tested on S. cerevisiae, polygodial proved to be fungicidal rather than fungistatic. When the cells of S. cerevisiae are treated in vitro with polygodial for 10 min, the cell membrane becomes severely damaged, and many vesicles, possibly formed from the fragmented cell membrane, can be observed within the cytoplasm.(In Vivo):Polygodial (0.1 to 10 mg kg(-1), i.p.) produced significant inhibition of acetic acid, kaolin and zymosan-induced writhing in mice, being about 14 to 27-fold more potent than the hydroalcoholic extract at the ID50 level.
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SynonymsTadeonal
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorTNF-α
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Research Area——
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Indication——
Chemical Information
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CAS Number6754-20-7
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Formula Weight234.3
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Molecular FormulaC15H22O2
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@@]12CC=C(C=O)[C@H](C=O)[C@@]1(C)CCCC2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cao Y, et al. Identification of a ligand for tumor necrosis factor receptor from Chinese herbs by combination of surface plasmon resonance biosensor and UPLC-MS. Anal Bioanal Chem. 2016 Jul;408(19):5359-67.
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