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Polmacoxib
CAS No. 301692-76-2
Polmacoxib ( CG-100649 )
Catalog No. M13942 CAS No. 301692-76-2
Polmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
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| 5MG | 58 | Get Quote |
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| 10MG | 98 | Get Quote |
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| 25MG | 165 | Get Quote |
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| 50MG | 245 | Get Quote |
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| 100MG | 357 | Get Quote |
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| 200MG | 534 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePolmacoxib
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NoteResearch use only, not for human use.
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Brief DescriptionPolmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II.
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DescriptionPolmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II; inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation; induces the G2/M cell cycle arrest in colon cancer cells, and inhibits the tumor growth in colon cancer xenograft in nude mice. Rheumatoid Arthritis Approved
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SynonymsCG-100649
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research AreaInflammation/Immunology
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IndicationRheumatoid Arthritis
Chemical Information
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CAS Number301692-76-2
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Formula Weight361.39
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Molecular FormulaC12H16FNO4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=CC=C(C(OC2(C)C)=C(C3=CC=CC(F)=C3)C2=O)C=C1)(N)=O
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Chemical Name4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Skarke C, et al. Clin Pharmacol Ther. 2012 Jun;91(6):986-93.
2. Kim SH, et al. Invest New Drugs. 2014 Dec;32(6):1105-1112.
3. Woo JK, et al. Oncol Rep. 2015 Apr;33(4):1947-55.
2. Kim SH, et al. Invest New Drugs. 2014 Dec;32(6):1105-1112.
3. Woo JK, et al. Oncol Rep. 2015 Apr;33(4):1947-55.
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