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Polaprezinc

CAS No. 107667-60-7

Polaprezinc ( Polaprezinc; Z 103 )

Catalog No. M17799 CAS No. 107667-60-7

Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 38 In Stock
25MG 60 In Stock
50MG 87 In Stock
100MG 133 In Stock
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Biological Information

  • Product Name
    Polaprezinc
  • Note
    Research use only, not for human use.
  • Brief Description
    Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
  • Description
    Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
  • Synonyms
    Polaprezinc; Z 103
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    107667-60-7
  • Formula Weight
    289.63
  • Molecular Formula
    C9H12N4O3Zn
  • Purity
    98%
  • Solubility
    H2O : 3.37 mg/mL 11.68 mM; DMSO : < 1 mg/mL
  • SMILES
    NCCC(=O)N1[Zn]OC(=O)[C@@H]1Cc1cnc[nH]1
  • Chemical Name
    catena-Poly(zinc-mu-(beta-alanyl-L-histidinato(2(-))-N,N(sup N),O:N(sup tau)))

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Odawara S, et al. Polaprezinc protects normal intestinal epithelium against exposure to ionizing radiation in mice. Mol Clin Oncol. 2016 Oct;5(4):377-381.
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