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Pivagabine

CAS No. 69542-93-4

Pivagabine ( CXB-722 )

Catalog No. M26382 CAS No. 69542-93-4

Pivagabine is a derivative of hydrophobic 4-aminobutyric acid, with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pivagabine
  • Note
    Research use only, not for human use.
  • Brief Description
    Pivagabine is a derivative of hydrophobic 4-aminobutyric acid, with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain.
  • Description
    Pivagabine is a derivative of hydrophobic 4-aminobutyric acid, with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain.(In Vivo):Pivagabine (CXB 722) (200 mg/kg; i.p.; twice a day for 4 days and 1 hour before killing on the 5th day) prevents the effects of foot-shock stress on CRF concentration in both brain regions.
  • Synonyms
    CXB-722
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Glutamate receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    69542-93-4
  • Formula Weight
    187.2
  • Molecular Formula
    C9H17NO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)C(=O)NCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Andersson M, et, al. Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia. Phytochemistry. 1995 Mar;38(4):835-6.
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