Pinocembrin

Research use only, not for human use.

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.(In Vitro):Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α.

Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α. Cell Viability Assay Cell Line:RBL-2H3 cells Concentration:5, 10, 25, 50, 100 or 200 μM Incubation Time:24 hours Result:Decreased cell viability by ～50% at ≥ 100 μM. Showed 75% cell viability at lower concentrations.

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(+)-Pinocoembrin | Dihydrochrysin | Galangin flavanone

Others

Other Targets

NF-κB

Inflammation/Immunology|Neurological Disease

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480-39-7

256.25

C15H12O4

>98% (HPLC)

DMSO : 125 mg/mL 487.80 mM

C1[C@H](Oc2cc(cc(c2C1=O)O)O)c1ccccc1

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(-20℃)

With Ice Pack

≥ 2 years