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Pimozide
CAS No. 2062-78-4
Pimozide ( NSC 170984; Orap; R 6238 )
Catalog No. M13205 CAS No. 2062-78-4
Pimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 41 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePimozide
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NoteResearch use only, not for human use.
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Brief DescriptionPimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor.
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DescriptionPimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor, also is an inhbitor of STAT5; also is a hERG blocker, inhibits USP1/UAF1 noncompetitively with Ki of 0.5 uM; displays selectivity against a number of deubiquitinases, deSUMOylase, and cysteine proteases.
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SynonymsNSC 170984; Orap; R 6238
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorD2;PotassiumChannel
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number2062-78-4
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Formula Weight461.56
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Molecular FormulaC28H29F2N3O
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C1N(C2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)C5=CC=CC=C5N1
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Chemical Name1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen J, et al. Chem Biol. 2011 Nov 23;18(11):1390-400.
2. Nelson EA, et al. Blood. 2011 Mar 24;117(12):3421-9.
3. Rondanin R, et al. ChemMedChem. 2017 Aug 8;12(15):1183-1190.
2. Nelson EA, et al. Blood. 2011 Mar 24;117(12):3421-9.
3. Rondanin R, et al. ChemMedChem. 2017 Aug 8;12(15):1183-1190.
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