Pimonidazole ( —— )

Catalog No. M24717 CAS No. 70132-50-2

Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Pimonidazole
Note

Research use only, not for human use.
Brief Description

Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group.
Description

Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

70132-50-2
Formula Weight

254.3
Molecular Formula

C11H18N4O3
Purity

>98% (HPLC)
Solubility

H2O:1 mg/mL (3.93 mM; Need ultrasonic)
SMILES

OC(CN1C=CN=C1[N+]([O-])=O)CN2CCCCC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7.

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