Picrocrocin( —— )

Catalog No. M21787 CAS No. 138-55-6

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Datasheet

HNMR

HPLC

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Product Name

Picrocrocin
Note

Research use only, not for human use.
Brief Description

Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells.
Description

Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells.
In Vitro

Picrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

138-55-6
Formula Weight

330.37
Molecular Formula

C??H??O?
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (302.69 mM)
SMILES

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2CC(C)(C(C=O)=C(C)C2)C
Chemical Name

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