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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - PfDHODH-IN-2

PfDHODH-IN-2

CAS No. 425629-94-3

PfDHODH-IN-2 ( —— )

Catalog No. M22750 CAS No. 425629-94-3

PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PfDHODH-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.
  • Description
    PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor .?It is used an antimalarial agent and can be used for the research of malaria.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    PfDHODH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    425629-94-3
  • Formula Weight
    297.76
  • Molecular Formula
    C13H12ClNO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:12 mg/mL?(40.3 mM;?Need ultrasonic)
  • SMILES
    CCOC(=O)C1=C(Nc2ccc(Cl)cc2)SCC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56(20):7911-24.
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