Cart
sales@molnova.com
PfDHODH-IN-2
CAS No. 425629-94-3
PfDHODH-IN-2 ( —— )
Catalog No. M22750 CAS No. 425629-94-3
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 222 | Get Quote |
|
| 25MG | 410 | Get Quote |
|
| 50MG | 605 | Get Quote |
|
| 100MG | 860 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePfDHODH-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionPfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.
-
DescriptionPfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor .?It is used an antimalarial agent and can be used for the research of malaria.
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorPfDHODH
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number425629-94-3
-
Formula Weight297.76
-
Molecular FormulaC13H12ClNO3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:12 mg/mL?(40.3 mM;?Need ultrasonic)
-
SMILESCCOC(=O)C1=C(Nc2ccc(Cl)cc2)SCC1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56(20):7911-24.
molnova catalog
related products
-
ASLAN003
ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
-
Isovaleramide
Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.
-
MF-438
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
