Pentostatin ( CI 825; CL 67310465; DCF; Deoxycoformycin; NSC 218321; NSC 247520 )

Catalog No. M14925 CAS No. 53910-25-1

Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase.

Purity : >98%(HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	72	In Stock
25MG	174	In Stock
50MG	324	In Stock
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Biological Information

Product Name

Pentostatin
Note

Research use only, not for human use.
Brief Description

Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase.
Description

Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase. This compound is effective against a variety of cancer cell lines.
Synonyms

CI 825; CL 67310465; DCF; Deoxycoformycin; NSC 218321; NSC 247520
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

Adenosine receptor
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

53910-25-1
Formula Weight

268.27
Molecular Formula

C11H16N4O4
Purity

>98%(HPLC)
Solubility

Water: 100 mM; DMSO: 75 mM
SMILES

O[C@H]1C2=C(N([C@H]3O[C@H](CO)[C@@H](O)C3)C=N2)N=CNC1
Chemical Name

(R)-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. nabhan, et Al. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era. Leukemia Res. 28 429.

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