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Pentostatin

CAS No. 53910-25-1

Pentostatin ( CI 825; CL 67310465; DCF; Deoxycoformycin; NSC 218321; NSC 247520 )

Catalog No. M14925 CAS No. 53910-25-1

Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 43 In Stock
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25MG 174 In Stock
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Biological Information

  • Product Name
    Pentostatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase.
  • Description
    Pentostatin is an extremely potent (Ki = 2.5 pM), irreversible inhibitor of adenosine deaminase. This compound is effective against a variety of cancer cell lines.
  • Synonyms
    CI 825; CL 67310465; DCF; Deoxycoformycin; NSC 218321; NSC 247520
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    Adenosine receptor
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    53910-25-1
  • Formula Weight
    268.27
  • Molecular Formula
    C11H16N4O4
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 100 mM; DMSO: 75 mM
  • SMILES
    O[C@H]1C2=C(N([C@H]3O[C@H](CO)[C@@H](O)C3)C=N2)N=CNC1
  • Chemical Name
    (R)-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. nabhan, et Al. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era. Leukemia Res. 28 429.
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