Panitumumab
CAS No. 339177-26-3
Panitumumab( —— )
Catalog No. M22158 CAS No. 339177-26-3
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 484 | In Stock |
|
10MG | 691 | In Stock |
|
25MG | 1035 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePanitumumab
-
NoteResearch use only, not for human use.
-
Brief DescriptionPanitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).
-
DescriptionPanitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).
-
In VitroWestern Blot Analysis Cell Line:EGFR-expressing NCI-H1975 cells, NCI-H1650 cells and CHO cells Concentration:2, 20, 200, 2000 nM Incubation Time:3 h Result:Inhibited ligand-induced autophosphorylation of EGFR.
-
In VivoAnimal Model:NCI-H1975 and NCI-H1650 xenografts Dosage:25, 100, or 500 μg/mouse Administration:Intraperitoneal injection (i.p.), twice a week Result:Inhibited ligand-induced EGFR phosphorylation, tumor growth, and markers of proliferation.Decreased Ki-67 and phospho- mitogen-activated protein kinase (pMAPK) staining in both xenografts.
-
Synonyms——
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorEGFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number339177-26-3
-
Formula Weight147 kDa
-
Molecular Formula——
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Cohenuram M, et al.Panitumumab the first fully human monoclonal antibody: from the bench to the clinic. Anticancer Drugs. 2007 Jan;18(1):7-15.
molnova catalog
related products
-
WHI-P258
WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3.
-
Leonurine hydrochlor...
Leonurine (hydrochloride), a major alkaloid compound extracted from?Leonurus japonicas?Houtt. (Labiatae), is considered to have antitumor roles.
-
(Rac)-JBJ-04-125-02
JBJ-04-125-02 is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.