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Home - Products - GPCR/G Protein - Antibacterial - Pactamycin

Pactamycin

CAS No. 23668-11-3

Pactamycin ( NSC 52947 )

Catalog No. M13681 CAS No. 23668-11-3

Pactamycin (NSC 52947) is a potent protein synthesis inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pactamycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Pactamycin (NSC 52947) is a potent protein synthesis inhibitor.
  • Description
    Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.
  • Synonyms
    NSC 52947
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    23668-11-3
  • Formula Weight
    558.62
  • Molecular Formula
    C28H38N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    InChI=1S/C28H38N4O8/c1-15-9-7-12-20(35)21(15)24(36)40-14-27(39)26(4,38)23(30-19-11-8-10-18(13-19)16(2)33)22(29)28(27,17(3)34)31-25(37)32(5)6/h7-13,17,22-23,30,34-35,38-39H,14,29H2,1-6H3,(H,31,37)
  • Chemical Name
    [(1S,2R,3R,4S,5S)-5-(3-acetylanilino)-4-amino-3-(dimethylcarbamoylamino)-1,2-dihydroxy-3-[(1S)-1-hydroxyethyl]-2-methylcyclopentyl]methyl 2-hydroxy-6-methylbenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bhuyan BK. Biochem Pharmacol. 1967 Aug;16(8):1411-20.
2. Suzuki H, et al. Proc Natl Acad Sci U S A. 1974 Oct;71(10):4259-63.
3. Kappen LS, et al. Biochemistry. 1976 Feb 24;15(4):811-8.
4. Hanessian S, et al. Bioorg Med Chem. 2013 Apr 1;21(7):1775-86.
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