PZ09

Research use only, not for human use.

PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM.

PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM, displays excellent selectivity (>200-fold) over other PKC isoforms with exception of PKC-i (10-fold); also shows high selectivity for CDK-2 (>200-fold), as well as a broader range of other kinases (<50% inhibition at 10 uM); PZ09 is a small-molecule inhibitor, the first tool to successfully interrogate aPKC signaling in cells.

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PKC-zeta inhibitor 9 | PKC-ζ inhibitor PZ9

Angiogenesis

PKC

PKC

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1132609-87-0

423.524

C25H25N7

>98% (HPLC)

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CN1CCN(CC1)C2=CC=CC3=C2N=C(N3)C4C5CCC(CC5NN4)C6=CC=C(C=C6)N

4-(3-(4-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-6-yl)aniline

(-20℃)

With Ice Pack

≥ 2 years