Cart
sales@molnova.com
PY-60
CAS No. 2765218-56-0
PY-60( —— )
Catalog No. M37636 CAS No. 2765218-56-0
PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 176 | Get Quote |
|
| 5MG | 273 | Get Quote |
|
| 10MG | 454 | Get Quote |
|
| 25MG | 726 | Get Quote |
|
| 50MG | 994 | Get Quote |
|
| 100MG | 1332 | Get Quote |
|
| 500MG | 2673 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePY-60
-
NoteResearch use only, not for human use.
-
Brief DescriptionPY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).
-
DescriptionPY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 μM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorYAP | Annexin A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2765218-56-0
-
Formula Weight313.37
-
Molecular FormulaC16H15N3O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (319.11 mM; Ultrasonic )
-
SMILESC(NCCCC1=NC=CS1)(=O)C=2C=C(ON2)C3=CC=CC=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Shalhout SZ, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nat Chem Biol. 2021;17(7):767-775.?
molnova catalog
related products
-
Lyticase
Lyticase, produced by a submerged culture of Arthrobacter luteus, is an enzyme preparation which effectively lyses cell walls of viable yeast cells. An essential enzyme responsible for lysis of viable yeast cells in this preparation is b-1, 3-glucan laminaripentaohydrolase.
-
3-Chloro-6-Bromo Ind...
3-Chloro-6-Bromo Indole is a marine derived natural products found in Ptychodera flava.
-
2-(Octyloxy)acetic a...
2-(Octyloxy)acetic acid is a fungal metabolite that accumulates in the growth medium of Acinetobacter.
