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PU23

CAS No. 817635-93-1

PU23( —— )

Catalog No. M29003 CAS No. 817635-93-1

PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    PU23
  • Note
    Research use only, not for human use.
  • Brief Description
    PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
  • Description
    PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).(In Vitro):6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. The combination of PU23 and 6-MP inhibits HEK293 and HEK293/MRP4 cells with IC50s of 1.84 and 6.06 μM, respectively.Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 h also significantly increases the amount of 6-MP in cells .
  • In Vitro
    6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. The combination of PU 23 (Cpd23) and 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 1.84 and 6.06 μM, respectively.Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 h also significantly increases the amount of 6-MP in cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    MRP
  • Recptor
    MRP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    817635-93-1
  • Formula Weight
    425.52
  • Molecular Formula
    C21H19N3O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (293.76 mM)
  • SMILES
    O=C(NC(=S)NC1=CC=C(C=C1)S(=O)(=O)NCC1=CC=CC=C1)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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