PSNCBAM-1
CAS No. 877202-74-9
PSNCBAM-1 ( PSNCBAM 1; PSNCBAM1 )
Catalog No. M27917 CAS No. 877202-74-9
PSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 133 | Get Quote |
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10MG | 195 | Get Quote |
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25MG | 323 | Get Quote |
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50MG | 480 | Get Quote |
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100MG | 692 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NamePSNCBAM-1
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NoteResearch use only, not for human use.
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Brief DescriptionPSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.
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DescriptionPSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.
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SynonymsPSNCBAM 1; PSNCBAM1
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number877202-74-9
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Formula Weight392.9
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Molecular FormulaC22H21ClN4O
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Purity>98% (HPLC)
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Solubility——
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SMILESClc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Otenabant
A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively; has low affinity (Ki=7600 nM) for human CB2 receptors; reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.ObesityPhase 3 Discontinued
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COR659
COR659 is a 2-acylaminothiophene derivative able to suppress alcohol and chocolate self-administration in rats, likely via positive allosteric modulation of the GABAB receptor and antagonism/inverse agonism at the cannabinoid CB1 receptor.
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PSNCBAM-1
PSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.