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PSB-603
CAS No. 1092351-10-4
PSB-603 ( PSB 603 )
Catalog No. M27690 CAS No. 1092351-10-4
Adenosine A2B receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 358 | Get Quote |
|
| 10MG | 533 | Get Quote |
|
| 25MG | 852 | Get Quote |
|
| 50MG | 1152 | Get Quote |
|
| 100MG | 1557 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePSB-603
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NoteResearch use only, not for human use.
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Brief DescriptionAdenosine A2B receptor antagonist.
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DescriptionAdenosine A2B receptor antagonist.(In Vitro):In peripheral T cells, PSB-603 (100 nM) inhibits NECA-stimulated IL-6 release about 3-fold. PSB-603 (10 μM) shows no affinity for the human and rat A1 and A2A and human A3 receptors.(In Vivo):PSB-603 (5 mg/kg; i.p.) significantly reduces inflammation in local and systemic mice models of inflammation. In the inflamed paw, PSB-603 significantly decreases the levels of the inflammatory cytokines including IL-6, TNF-α and of ROS. PSB-603 reduces inflammation of the peritoneum by decreasing the infiltration of leukocytes.
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SynonymsPSB 603
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1092351-10-4
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Formula Weight529.0
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Molecular FormulaC24H25ClN6O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCn1c(O)nc2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.
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