Cart
sales@molnova.com
PRX-08066
CAS No. 866206-54-4
PRX-08066 ( —— )
Catalog No. M24869 CAS No. 866206-54-4
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 110 | In Stock |
|
| 10MG | 160 | In Stock |
|
| 25MG | 332 | In Stock |
|
| 50MG | 494 | In Stock |
|
| 100MG | 709 | In Stock |
|
| 500MG | 1467 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePRX-08066
-
NoteResearch use only, not for human use.
-
Brief DescriptionPRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
-
DescriptionPRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor5-HT2B
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number866206-54-4
-
Formula Weight401.9
-
Molecular FormulaC19H17ClFN5S
-
Purity>98% (HPLC)
-
SolubilityDMSO:7 mg/mL (17.42 mM; Need ultrasonic)
-
SMILESC1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Porvasnik SL, et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72.
molnova catalog
related products
-
Geissoschizine methy...
Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist.
-
NAN-190 hydrobromide
NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
-
Olopatadine hydrochl...
Olopatadine hydrochloride is a histamine blocker used to treat allergic conjunctivitis.
