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PPTN hydrochloride
CAS No. 1992047-65-0
PPTN hydrochloride( —— )
Catalog No. M35725 CAS No. 1992047-65-0
PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist (KB: 434 pM) with no agonist or antagonist activity at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors, exhibiting anti-inflammatory and anti-immune effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 62 | Get Quote |
|
| 5MG | 92 | Get Quote |
|
| 10MG | 155 | Get Quote |
|
| 25MG | 296 | Get Quote |
|
| 50MG | 457 | Get Quote |
|
| 100MG | 651 | Get Quote |
|
| 500MG | 1368 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePPTN hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist (KB: 434 pM) with no agonist or antagonist activity at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors, exhibiting anti-inflammatory and anti-immune effects.
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DescriptionPPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetP2Y Receptor
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RecptorP2Y Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1992047-65-0
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Formula Weight511.96
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Molecular FormulaC29H25ClF3NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (488.32 mM; Ultrasonic )
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SMILESCl.OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Barrett MO, et al. A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils. Mol Pharmacol. 2013 Jul;84(1):41-9.?
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