PP2
CAS No. 172889-27-9
PP2 ( AGL 1879 )
Catalog No. M12625 CAS No. 172889-27-9
PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 35 | In Stock |
|
5MG | 57 | In Stock |
|
10MG | 106 | In Stock |
|
25MG | 178 | In Stock |
|
50MG | 304 | In Stock |
|
100MG | 482 | In Stock |
|
200MG | 687 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePP2
-
NoteResearch use only, not for human use.
-
Brief DescriptionPP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM.
-
DescriptionPP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.
-
SynonymsAGL 1879
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorEGFR; JAK2; Fyn; Lck; ZAP70
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number172889-27-9
-
Formula Weight301.77
-
Molecular FormulaC15H16ClN5
-
Purity>98%(HPLC)
-
SolubilityEthanol: 2 mg/mL (6.62 mM); DMSO: 60 mg/mL (198.82 mM)
-
SMILESNC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(Cl)C=C3)=NC=N1
-
Chemical Name1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hanke JH, et al. J Biol Chem, 1996, 271(2), 695-70
molnova catalog
related products
-
Epidermal Growth Fac...
Epidermal Growth Factor?binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.
-
Nimotuzumab
Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).
-
Matuzumab
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR frequently associated with the growth of blood vessels in malignancy facilitating tumor growth and survival.