PP2

CAS No. 172889-27-9

PP2 ( AGL 1879 )

Catalog No. M12625 CAS No. 172889-27-9

PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 In Stock
5MG 57 In Stock
10MG 106 In Stock
25MG 178 In Stock
50MG 304 In Stock
100MG 482 In Stock
200MG 687 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PP2
  • Note
    Research use only, not for human use.
  • Brief Description
    PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM.
  • Description
    PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.
  • Synonyms
    AGL 1879
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR; JAK2; Fyn; Lck; ZAP70
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    172889-27-9
  • Formula Weight
    301.77
  • Molecular Formula
    C15H16ClN5
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 2 mg/mL (6.62 mM); DMSO: 60 mg/mL (198.82 mM)
  • SMILES
    NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(Cl)C=C3)=NC=N1
  • Chemical Name
    1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hanke JH, et al. J Biol Chem, 1996, 271(2), 695-70
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