PP1

CAS No. 172889-26-8

PP1( AGL 1872 | EI 275 )

Catalog No. M12624 CAS No. 172889-26-8

PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 73 In Stock
10MG 109 In Stock
25MG 191 In Stock
50MG 267 In Stock
100MG 421 In Stock
500MG 945 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PP1
  • Note
    Research use only, not for human use.
  • Brief Description
    PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM.
  • Description
    PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AGL 1872 | EI 275
  • Pathway
    Tyrosine Kinase
  • Target
    Bcr-Abl
  • Recptor
    Bcr-Abl| Kit| EGFR| Fyn| Lck
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    172889-26-8
  • Formula Weight
    281.36
  • Molecular Formula
    C16H19N5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:4 mg/mL (14.21 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(C)C=C3)=NC=N1
  • Chemical Name
    1-(tert-butyl)-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hanke JH, et al. J Biol Chem, 1996, 271(2), 695-701.
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